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Thymogen/122933-59-9/Thymogen Peptide

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  • Product Description

PeptideNameThymogen/122933-59-9/Thymogen Peptide

Catalog  NoGT-N251

SequenceH-Glu-Trp-OH

CAS Number122933-59-9

Molecular FormulaC16H19N3O5

Molecular Weight333.35

CategoryThymogen,122933-59-9,Peptide synthesis,Peptide raw material company

Thymogen

DescriptionThymogen achieves broad-spectrum immune enhancement and anti-inflammatory balance by regulating the secretion of cytokines such as IL-2, IFN-γ, and TNF-α, promoting the balance of CD4⁺/CD8⁺ T cell subsets, and enhancing the chemotaxis and phagocytic activity of neutrophils. It is mainly used for the adjuvant intervention of immunodeficiency, chronic infections, and immune damage caused by radiotherapy and chemotherapy in clinical and scientific research, while exhibiting potential in anti-angiogenesis, neuroprotection, and tissue repair.

 

Specifications

Apperance: White to off-white powder

Purity(HPLC): ≥98.0%

Single Impurity: ≤2.0%

Acetate Content(HPLC): 5.0%12.0%

Water Content (Karl Fischer): ≤10.0%

Peptide Content: ≥80.0%

Packing and Shipping: Low temperature, vacuum packing, accurate to mg as required.

 

FAQ

Were the peptides containing Cys reduced before shipment?

If the peptide is not found to have been oxidized, we generally do not reduce Cys. All polypeptides are obtained from crude products purified and lyophilized under pH2 conditions, which at least to some extent prevent the oxidation of Cys. Peptides containing Cys are purified at pH2 unless there is a specific reason to purify at pH6.8. If purification is performed at pH6.8, the purified product must be treated with acid immediately to prevent oxidation. In the final quality control step, for the peptides containing Cys, if the presence of molecular weight (2P+H) substance is found on the MS map, it indicates that a dimer has been formed. If there is no problem with MS and HPLC, we will directly lyophilize and ship the goods without any further processing. It should be noted that peptides containing Cys undergo slow oxidation over time, and the degree of oxidation depends on peptide sequence and storage conditions.

Thymogen

How is my peptide transported? What test reports are provided?

All freeze-dried polypeptides are usually stored in special containers of 2 ml or 10ml with original analytical data and synthesis reports containing important information such as sequence, molecular weight, purity, weight, and number of the polypeptide.

 

If a Thymogen is 98% pure, what is 2%?

Two percent of the composition was truncated or deleted sequence fragments.

 

How do you determine if a peptide is looped?

We use the Ellman reaction to test whether the ring formation is complete. If the Ellman test is positive (yellow), the ring reaction is incomplete. If the test results are negative (not yellow), the ring reaction has been complete. We do not provide the analysis report of cyclization identification for our clients. Generally, there will be a description of Ellman's test results in the QC report.

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